Tivozanib-d6 is a deuterium-labeled form of Tivozanib, a selective inhibitor of vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, and VEGFR-3), demonstrating IC50 values of 30 nM, 6.5 nM, and 15 nM, respectively. This reagent is employed in chemical research to track the metabolism and pharmacokinetics of Tivozanib in various biological systems. Its application is particularly relevant in studies focused on tumor growth inhibition and angiogenesis modulation, enhancing understanding of targeted cancer therapies.
Tivozanib-d6 is a deuterium-labeled form of Tivozanib, a selective inhibitor of vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, and VEGFR-3), demonstrating IC50 values of 30 nM, 6.5 nM, and 15 nM, respectively. This reagent is employed in chemical research to track the metabolism and pharmacokinetics of Tivozanib in various biological systems. Its application is particularly relevant in studies focused on tumor growth inhibition and angiogenesis modulation, enhancing understanding of targeted cancer therapies.
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