Fig. 1 · Structure
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TJ-M2010-5
MyD88 Inhibitor
TJ-M2010-5 is a MyD88 inhibitor that disrupts homodimerization through binding to the TIR domain of MyD88, thereby modulating the TLR/MyD88 signaling pathway. This compound is particularly relevant for investigating the mechanisms underlying myocardial ischemia/reperfusion injury (MIRI) and can aid in the development of therapeutic strategies targeting inflammatory responses associated with this condition. It serves as a valuable tool for research into immune signaling and cardiovascular protection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1357471-57-8 |
| Applications | MyD88 Inhibitor |
| Formula | C23H26N4OS |
| Molecular Weight | 406.54 |
| SMILES | O=C(NC1=NC(C2=CC=CC=C2)=CS1)CCN3CCN(CC4=CC=CC=C4)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.