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TJN 220

Anti-hypertensive Agent

TJN 220 is a synthetic derivative of tetrandrine, functioning as an anti-hypertensive agent. It exhibits a long-lasting and stable reduction in blood pressure across various hypertension models, making it particularly effective for managing nighttime hypertension. Notably, TJN 220 does not induce reflex tachycardia, which enhances its therapeutic profile. This compound is suitable for research applications focused on the mechanisms and treatments of hypertension.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	118160-59-1
Applications	Anti-hypertensive Agent
Formula	C₃₉H₄₄N₂O₆
Molecular Weight	636.78
SMILES	CCOC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(OC5=CC=C(C[C@@]6([H])C7=CC(O2)=C(C=C7CCN6C)OC)C=C5)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.