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TLR7/8 agonist 12-PAB-(PEG4-Me)-Cit-Val-PEG2-amide-C2-MC

Linker-Payload Conjugate

TLR7/8 agonist 12-PAB-(PEG4-Me)-Cit-Val-PEG2-amide-C2-MC is a linker-payload conjugate designed for the synthesis of antibody-drug conjugates (ADCs). This compound targets Toll-like receptors 7 and 8, enhancing immune response through the activation of innate immune pathways. Its biological activity facilitates targeted therapy and immunomodulation in cancer research, making it a valuable tool for developing ADCs with potent payloads and effective linkers.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3080930-77-1
Applications	Linker-Payload Conjugate
Formula	C₇₂H₁₀₂N₁₄O₁₉
Molecular Weight	1467.66
SMILES	CCC[C@H](NC1=NC(N)=NC2=C1N(C3=C2C=CC=C3)CC4=C(C=CC(CN(C(OCC5=C(C(NCCOCCOCCOCCOC)=O)C=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCNC(CCN6C(C=CC6=O)=O)=O)=O)=O)=O)C=C5)=O)[C@H]7CCOC7)=C4)OC)CCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.