Fig. 1 · Structure
Documents & Downloads
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
Drug-Linker Conjugate
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride is a drug-linker conjugate that specifically targets Toll-like receptors 7 and 8. This compound demonstrates significant antitumor activity, leveraging the immunostimulatory properties of TLR7/8 agonist 4, which is attached through a non-cleavable linker, hydroxy-PEG10-acid. This reagent is valuable for research applications in antibody-drug conjugate (ADC) development, particularly in enhancing immune-mediated tumor cell clearance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2388520-36-1 |
| Applications | Drug-Linker Conjugate |
| Formula | C41H69ClN6O12 |
| Molecular Weight | 873.47 |
| SMILES | CCCCC(NC1=C2C(C=CC(N(CC3)CCN3CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=C2)=N4)=NC1=C4N.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.