Fig. 1 · Structure

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TLR7/8 agonist 4 hydroxy-PEG6-acid

Drug-Linker Conjugate

TLR7/8 agonist 4 hydroxy-PEG6-acid serves as a drug-linker conjugate for antibody-drug conjugate (ADC) development. This compound combines the TLR7/8 agonist 4 with a non-cleavable linker, Hydroxy-PEG6-acid, facilitating the targeted delivery of therapeutic agents to immune cells. Its unique design enhances immune activation and provides a platform for the synthesis of effective ADCs, making it valuable for research in cancer immunotherapy and targeted treatment strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2388520-23-6
Applications Drug-Linker Conjugate
Formula C33H52N6O8
Molecular Weight 660.80
SMILES
O=C(CCOCCOCCOCCOCCOCCOCCN1CCN(CC1)C2=CC3=C(N=C(C4=C3NC(CCCC)=N4)N)C=C2)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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