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TMLZ-G46

ZNF207 Inhibitor

TMLZ-G46 is a potent inhibitor of ZNF207, demonstrating an affinity with a Kd value of 68 nM and the ability to penetrate the blood-brain barrier. This compound effectively inhibits cancer cell proliferation, stemness, migration, and invasion while inducing G0/G1 cell cycle arrest and apoptosis. TMLZ-G46 is particularly relevant for research applications focused on glioma.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3116767-83-7
Applications	ZNF207 Inhibitor
Formula	C₃₇H₄₁N₃O₃
Molecular Weight	575.74
SMILES	O=C(/C(C#N)=C1C2=CC=CC=C2OC3=CC=CC=C3\1)NCCC4CCN(CC4)CC5=CC=C(C=C5)OCC6CCCCC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.