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TNKS 22

Tankyrase Inhibitor

TNKS 22 is a selective inhibitor of tankyrase 1 and tankyrase 2. It demonstrates potent inhibitory activity, with IC50 values of 0.1 nM and 4.1 nM for TNKS1 and TNKS2, respectively. This compound serves as a valuable tool for research into the roles of tankyrases in cellular processes such as the Wnt signaling pathway and telomere regulation. Applications include studies in cancer biology and therapeutic development targeting poly(ADP-ribose) polymerase pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1507362-00-6
Applications	Tankyrase Inhibitor
Formula	C₂₅H₂₅N₅O₃S
Molecular Weight	475.56
Synonyms	TNKS-IN-22
SMILES	O=C1C2=CC=CC=C2NC(SCCC(N[C@@H]3CC[C@@H](C4=NN=C(C5=CC=CC=C5)O4)CC3)=O)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.