Fig. 1 · Structure

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TNKS modulator-1

TNKS Modulator

TNKS modulator-1 is a small molecule targeting tankyrase (TNKS) enzymes. This compound inhibits TNKS activities, resulting in the stabilization of β-catenin and modulation of Wnt signaling pathways. Its primary applications include research in cancer biology and regenerative medicine, particularly in studying tumor growth and cellular signaling mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 873075-19-5
Applications TNKS Modulator
Formula C18H11NO4
Molecular Weight 305.28
SMILES
O=C(OCC#N)C1=CC=C(C2=CC(C3=C(O2)C=CC=C3)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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