Fig. 1 · Structure
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Toborinone
Inotropic Agent
Toborinone is an inotropic agent that primarily acts by inhibiting phosphodiesterase (PDE), leading to increased levels of cyclic AMP (cAMP) and intracellular calcium. This compound is known for its ability to enhance cardiac contractility and has applications in studying cardiovascular function. Additionally, Toborinone effectively inhibits thrombin-induced platelet aggregation, exhibiting an IC50 value of 9.7 μM, making it relevant for research into thrombotic disorders and platelet biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 143343-83-3 |
| Applications | Inotropic Agent |
| Formula | C21H24N2O5 |
| Molecular Weight | 384.43 |
| SMILES | COC1=C(C=CC(CNCC(COC2=CC=C3C(C=CC(N3)=O)=C2)O)=C1)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.