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Tofacitinib-d3 citrate

Catalog No.: A30838
Stable Isotope
Tofacitinib-d3 citrate is a deuterated form of Tofacitinib citrate, serving as a stable isotope labeling reagent. This compound functions as a selective inhibitor of Janus kinases (JAK1, JAK2, and JAK3) with IC50 values of 1 nM, 20 nM, and 112 nM, respectively. Tofacitinib citrate exhibits significant antibacterial, antifungal, and antiviral activities, making it valuable for studies in immunology, infectious disease, and pharmacology. Its isotopic labeling allows for precise tracking and quantification in biological research.
Tofacitinib-d3 citrate 2701680-77-3 Stable Isotope
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1mg
$865.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTofacitinib-d3 citrate is a deuterated form of Tofacitinib citrate, serving as a stable isotope labeling reagent. This compound functions as a selective inhibitor of Janus kinases (JAK1, JAK2, and JAK3) with IC50 values of 1 nM, 20 nM, and 112 nM, respectively. Tofacitinib citrate exhibits significant antibacterial, antifungal, and antiviral activities, making it valuable for studies in immunology, infectious disease, and pharmacology. Its isotopic labeling allows for precise tracking and quantification in biological research.
Product Information
Catalog NumA30838
FormulaC22H25D3N6O8
Molecular Weight507.51
CAS Number2701680-77-3
SMILESO=C(CC#N)N1C[C@H](N(C2=C3C(NC=C3)=NC=N2)C([2H])([2H])[2H])[C@H](C)CC1.O=C(CC(C(O)=O)(O)CC(O)=O)O
SynonymsTasocitinib-d3 citrate; CP-690550-d3 citrate
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Isotope-Labeled Compounds