Tofogliflozin (hydrate)

Catalog No.: A17860

SGLT2 inhibitor

Tofogliflozin (hydrate)

Tofogliflozin (hydrate) Chemical Structure

CAS NO. 1201913-82-7

Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$155.00
50 mg
$460.00
100 mg
$920.00
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Biological Activity

Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.72 mL 123.62 mL 247.25 mL
0.5 mM 4.94 mL 24.72 mL 49.45 mL
1 mM 2.47 mL 12.36 mL 24.72 mL
5 mM 0.49 mL 2.47 mL 4.94 mL

*The above data is based on the productmolecular weight 404.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17860
Actions Inhibitor
M. Wt 404.45
Formula C22H28O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1201913-82-7
Synonyms CSG-452 hydrate, CSG452, CSG 452
SMILES O[[email protected]@H]1[[email protected]@H](O)[[email protected]](O)[[email protected]@H](CO)O[[email protected]@]21OCC3=C2C=C(CC4=CC=C(CC)C=C4)C=C3.O

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