Tos-PEG6-acid is a PEG linker featuring a tosyl group and a terminal carboxylic acid, designed for biochemical assay applications. The hydrophilic PEG spacer enhances solubility in aqueous environments, while the tosyl group serves as an excellent leaving group for nucleophilic substitution reactions. The terminal carboxylic acid readily reacts with primary amines in the presence of activators, such as HATU, facilitating the formation of stable amide bonds for various bioconjugation strategies.
Tos-PEG6-acid is a PEG linker featuring a tosyl group and a terminal carboxylic acid, designed for biochemical assay applications. The hydrophilic PEG spacer enhances solubility in aqueous environments, while the tosyl group serves as an excellent leaving group for nucleophilic substitution reactions. The terminal carboxylic acid readily reacts with primary amines in the presence of activators, such as HATU, facilitating the formation of stable amide bonds for various bioconjugation strategies.
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