Fig. 1 · Structure
Documents & Downloads
TP-040
OGA Inhibitor
TP-040 is a potent inhibitor of O-GlcNAcase (OGA), exhibiting an IC50 value of 46 nM. This compound serves as a valuable chemical probe in the study of O-GlcNAcylation and its regulatory effects in cellular processes. Its application in research supports investigations into metabolic diseases, neurodegenerative disorders, and cancer mechanisms, making it a critical tool for elucidating the role of OGA in various biological contexts.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2757254-99-0 |
| Applications | OGA Inhibitor |
| Formula | C15H22N6 |
| Molecular Weight | 286.38 |
| Synonyms | O-GlcNAcase-IN-1 |
| SMILES | CC1CCN(C2=NC(NCC3=CN(C)C=N3)=NC=C2)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.