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TP-061

Brr2 Inhibitor

TP-061 is a selective inhibitor of the Brr2 ATPase, demonstrating an IC50 value of 42 nM. This compound effectively disrupts the function of Brr2, which is essential for the assembly of spliceosomal complexes. TP-061 is valuable for research applications focused on RNA splicing and the characterization of splicing-related mechanisms in eukaryotic cells.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2133440-09-0
Applications	Brr2 Inhibitor
Formula	C₂₁H₂₅FN₄O₂
Molecular Weight	384.45
SMILES	O=C1NC2=C(C=C(F)C=C2)[C@]13N(C(C4=CN(C)C=N4)=O)[C@@H](CC(C)C)C[C@H]3C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.