TP0463518

Catalog No.: A20183

PHD inhibitor

TP0463518

TP0463518 Chemical Structure

CAS NO. 1558021-37-6

TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $420.00

Special Price $336.00

10 mg

Regular Price: $700.00

Special Price $560.00

50 mg

Regular Price: $2,100.00

Special Price $1,680.00

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Biological Activity

TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2.
In vitro DMSO 34 mg/mL (78.73 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.16 mL 115.79 mL 231.57 mL
0.5 mM 4.63 mL 23.16 mL 46.31 mL
1 mM 2.32 mL 11.58 mL 23.16 mL
5 mM 0.46 mL 2.32 mL 4.63 mL

*The above data is based on the productmolecular weight 431.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20183
Actions Inhibitor
CAS No. 1558021-37-6
Formula C20H18ClN3O6
M. Wt 431.83
Purity >98%
Synonyms TP 0463518, TP-0463518
SMILES ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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