Biological Activity
TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.16 mL | 115.79 mL | 231.57 mL |
0.5 mM | 4.63 mL | 23.16 mL | 46.31 mL |
1 mM | 2.32 mL | 11.58 mL | 23.16 mL |
5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
*The above data is based on the productmolecular weight 431.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A20183 |
---|---|
Actions | Inhibitor |
M. Wt | 431.83 |
Formula | C20H18ClN3O6 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1558021-37-6 |
Synonyms | TP 0463518, TP-0463518 |
SMILES | ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2 |
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