TP53 neoepitope is a high-affinity antigenic peptide that targets HLA-A molecules. It is designed to elicit CD8+ T cell-mediated cytotoxicity against tumor cells harboring TP53 mutations, specifically hotspot mutations such as R175H and R273H. This peptide is promising for research applications in the immunotherapy of solid tumors with TP53 alterations, providing insights into potential therapeutic interventions targeting mutant TP53 pathways.
TP53 neoepitope is a high-affinity antigenic peptide that targets HLA-A molecules. It is designed to elicit CD8+ T cell-mediated cytotoxicity against tumor cells harboring TP53 mutations, specifically hotspot mutations such as R175H and R273H. This peptide is promising for research applications in the immunotherapy of solid tumors with TP53 alterations, providing insights into potential therapeutic interventions targeting mutant TP53 pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
