Fig. 1 · Structure
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Tpl2-IN-I
MAP3K Inhibitor
Tpl2-IN-I is a selective inhibitor of the Tpl2 (tumor progression locus 2) kinase, a key regulator in MAPK signaling pathways. This compound exhibits potential anti-inflammatory and anti-tumor properties, making it relevant for studies related to cancer progression and immune response modulation. Researchers can utilize Tpl2-IN-I to explore the role of Tpl2 in various cellular processes and disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 915009-13-1 |
| Applications | MAP3K Inhibitor |
| Formula | C21H14ClFN6 |
| Molecular Weight | 404.83 |
| SMILES | N#CC1=C(NC2=CC=C(F)C(Cl)=C2)C3=CC(N(C)C4=CC=CN=C4)=NC=C3N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.