Fig. 1 · Structure
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Tpl2 Kinase Inhibitor 1
Tpl2/COT/MAP3K8 Inhibitor
Tpl2 Kinase Inhibitor 1 targets Tpl2/COT/MAP3K8, functioning as a selective inhibitor with an IC50 of 50 nM. This compound modulates key pathways involved in the inflammatory response and plays a significant role in cancer progression. Its unique mechanism makes it valuable for research exploring cytokine signaling and tumor biology. Tpl2 Kinase Inhibitor 1 is useful in studies aimed at understanding inflammatory diseases and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 871307-18-5 |
| Applications | Tpl2/COT/MAP3K8 Inhibitor |
| Formula | C21H14ClFN6 |
| Molecular Weight | 404.83 |
| SMILES | N#CC1=C(NC2=CC=C(F)C(Cl)=C2)C3=CC(NCC4=CC=CN=C4)=NC=C3N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.