Fig. 1 · Structure
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Trachelogenin
HCV Entry Inhibitor
Trachelogenin is a potent hepatitis C virus (HCV) entry inhibitor that demonstrates low cytotoxicity and genotype-independent activity. It effectively inhibits HCV cell culture (HCVcc) infection and HCV pseudoparticle (HCVpp) entry in a dose-dependent manner, with IC50 values of 0.325 μg/mL and 0.259 μg/mL, respectively. In addition to its antiviral properties, Trachelogenin also exhibits significant anti-inflammatory and analgesic effects, making it a valuable tool for research in HCV-related studies and potential therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 34209-69-3 |
| Applications | HCV Entry Inhibitor |
| Formula | C21H24O7 |
| Molecular Weight | 388.41 |
| Synonyms | (-)-Trachelogenin |
| SMILES | O[C@]1([C@H](COC1=O)CC(C=C2)=CC(OC)=C2OC)CC(C=C3)=CC(OC)=C3O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.