Fig. 1 · Structure

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Trandolapril-d5

ACE Inhibitor

Trandolapril-d5 is a deuterated form of Trandolapril, a potent angiotensin-converting enzyme (ACE) inhibitor. It is utilized in the management of hypertension and congestive heart failure (CHF) through the inhibition of the ACE enzyme, which plays a crucial role in the renin-angiotensin-aldosterone system. This labeled reagent is valuable for pharmacokinetic studies and metabolic research involving Trandolapril.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1356847-98-7
Applications ACE Inhibitor
Formula C24H29D5N2O5
Molecular Weight 435.57
Synonyms RU44570 d5
SMILES
O=C([C@H]1N(C([C@@H](N[C@H](C(OCC)=O)CCC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C)=O)[C@@]3([H])CCCC[C@]3([H])C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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