Fig. 1 · Structure

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Trandolaprilate-d5

ACE Inhibitor

Trandolaprilate-d5 is a deuterium-labeled derivative of Trandolaprilate, serving as an angiotensin-converting enzyme (ACE) inhibitor. This compound exhibits effective inhibition of ACE activity, thereby contributing to the regulation of blood pressure and fluid balance. It is utilized in research to explore cardiovascular physiology, hypertension treatment mechanisms, and pharmacokinetics involving deuterated compounds.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1356841-27-4
Applications ACE Inhibitor
Formula C22H25D5N2O5
Molecular Weight 407.51
Synonyms Trandolaprilat d5; RU 44403 d5
SMILES
O=C([C@H]1N(C([C@@H](N[C@H](C(O)=O)CCC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C)=O)[C@@]3([H])CCCC[C@]3([H])C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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