Fig. 1 · Structure
Documents & Downloads
(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
Ribonuclease Activator
(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane acts as a dithiol catalyst that mimics protein disulfide isomerase (PDI) activity. This compound significantly enhances protein folding by facilitating the activation of scrambled ribonuclease A and promoting the formation of native disulfide bonds. Additionally, when used in the culture medium of Saccharomyces cerevisiae, it can increase the secretion of Schizosaccharomyces pombe acid phosphatase by over threefold. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane is valuable for research in protein production and secretion methodologies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 257641-01-3 |
| Applications | Ribonuclease Activator |
| Formula | C10H18N2O2S2 |
| Molecular Weight | 262.39 |
| SMILES | SCC(N[C@H]1[C@@H](CCCC1)NC(CS)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.