Fig. 1 · Structure
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trans-2-Decenal
Helicobacter pylori urease Inhibitor
trans-2-Decenal is a potent urease inhibitor targeting Helicobacter pylori, exhibiting an IC50 of 9.484 μg/mL. This compound demonstrates significant antibacterial activity against H. pylori, reducing urease activity and impacting bacterial morphology by inducing cell rupture, inhibiting biofilm formation, and decreasing migratory capabilities. Additionally, trans-2-Decenal disrupts cellular integrity in Phytophthora capsici, triggering reactive oxygen species accumulation and impairing mitochondrial function. Its applications extend to research on Helicobacter pylori and plant diseases associated with Phytophthora capsici.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3913-81-3 |
| Applications | Helicobacter pylori urease Inhibitor |
| Formula | C10H18O |
| Molecular Weight | 154.25 |
| Synonyms | (E)-Dec-2-enal |
| SMILES | CCCCCCC/C=C/C=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.