Fig. 1 · Structure
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trans-Platinum(II)diammine dichloride
DNA Crosslinker
Trans-Platinum(II)diammine dichloride is a DNA cross-linking agent that targets DNA to induce cross-link damage with relatively low cytotoxicity. This geometric isomer of Cisplatin is valuable for research investigating DNA-protein interactions and the mechanisms of DNA repair. Its unique properties make it a significant tool for studies involving cellular responses to DNA damage and therapeutic applications in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 14913-33-8 |
| Applications | DNA Crosslinker |
| Formula | Cl2H6N2Pt |
| Molecular Weight | 300.05 |
| Synonyms | trans-platinumdiamminedichloride |
| SMILES | Cl[Pt]Cl.N.N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.