Fig. 1 · Structure
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Traxanox
Diuretic
Traxanox is an orally available diuretic that enhances phagocytosis of yeast granules by mouse peritoneal macrophages and rat peritoneal polymorphonuclear leukocytes in vitro. This compound effectively inhibits IgE-mediated histamine release and cyclic AMP phosphodiesterase activity, demonstrating significant anti-inflammatory properties. Traxanox reduces pleural fluid accumulation in experimental models of inflammation and exhibits a synergistic effect with hydrocortisone or indomethacin in suppressing adjuvant arthritis in rats, making it a valuable tool for researching diuretic and anti-inflammatory mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 58712-69-9 |
| Applications | Diuretic |
| Formula | C13H6ClN5O2 |
| Molecular Weight | 299.67 |
| SMILES | O=C1C2=CC=CN=C2OC3=C1C=C(C4=NN=NN4)C=C3Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.