Fig. 1 · Structure
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Traxoprodil
iGluR Antagonist
Traxoprodil is a selective antagonist of the NMDA receptor, primarily targeting the ionotropic glutamate receptor (iGluR) subtype. It demonstrates neuroprotective effects on hippocampal neurons, with an IC50 value of 10 nM. This compound is widely utilized in research applications related to neuroprotection, neurodegenerative diseases, and synaptic plasticity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 134234-12-1 |
| Applications | iGluR Antagonist |
| Formula | C20H25NO3 |
| Molecular Weight | 327.42 |
| Synonyms | CP101,606 |
| SMILES | OC1(C2=CC=CC=C2)CCN([C@@H](C)[C@@H](O)C3=CC=C(O)C=C3)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.