Fig. 1 · Structure
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Trazpiroben
Dopamine D2/D3 Receptor Antagonist
Trazpiroben is a selective antagonist of the dopamine D2 and D3 receptors, primarily utilized for investigating the pathophysiology and treatment of moderate-to-severe gastroparesis. Its inhibition of these receptors plays a significant role in regulating gastrointestinal motility. Trazpiroben is a valuable tool for researchers exploring the therapeutic potential and underlying mechanisms of dopamine-related gastrointestinal disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1352993-39-5 |
| Applications | Dopamine D2/D3 Receptor Antagonist |
| Formula | C31H39N3O4 |
| Molecular Weight | 517.66 |
| Synonyms | TAK-906 |
| SMILES | O=C(O)C1=CC=CC(CN2CN(C3CCCCC3)C4(CCN(CCCC(C5=CC=CC=C5)=O)CC4)C2=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.