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Biological Activity
TRC 051384, belonging to substituted 2-propen-1-one class, is a potent inducer of heat shock protein 70 (HSP70) [1]. Induction of HSP70 is a natural response of stressed cells that protects neuronal cells from a variety of insults including acute ischemia.
| In vitro | DMSO | 86 mg/mL (184.72 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (10.74 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.48 mL | 107.4 mL | 214.8 mL |
| 0.5 mM | 4.3 mL | 21.48 mL | 42.96 mL |
| 1 mM | 2.15 mL | 10.74 mL | 21.48 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
*The above data is based on the productmolecular weight 465.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16053 |
|---|---|
| Actions | Inducer |
| CAS No. | 867164-40-7 |
| Formula | C25H31N5O4 |
| M. Wt | 465.54 |
| Purity | >98% |
| Synonyms | TRC051384, TRC-051384 |
| SMILES | O=C(C1=CC=C(N/C(O)=N/CCN2CCOCC2)C=C1)/C([H])=C([H])/C3=NC(N4CCOCC4)=CC=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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