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TRC4186

AGE Inhibitor

TRC4186 is a potent inhibitor of advanced glycation end-products (AGEs), targeting the accumulation of AGEs that contribute to diabetic complications. In vitro studies indicate that TRC4186 exhibits AGE-breaking activity, while animal models demonstrate its efficacy in enhancing endothelial and myocardial function in diabetes mellitus. This compound is valuable for research focused on the pathophysiology of diabetes-related complications and interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	357625-50-4
Applications	AGE Inhibitor
Formula	C₁₃H₁₄ClN₃O₄S₂
Molecular Weight	375.85
SMILES	O=C(C1=CC=C[N+](CC(C2=CC=CS2)=O)=C1)NNS(=O)(C)=O.[Cl-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.