Fig. 1 · Structure
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TREX1-IN-1
TREX1 Inhibitor
TREX1-IN-1 is a potent inhibitor of the TREX1 enzyme, demonstrating an IC50 value for human TREX1 of less than 0.1 μM. This compound effectively modulates TREX1 activity, making it a valuable tool for studying its role in DNA sensing and immune regulation. TREX1-IN-1 is applicable in research focused on autoimmunity, cancer, and inflammatory responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2756594-27-9 |
| Applications | TREX1 Inhibitor |
| Formula | C19H18FN3O5 |
| Molecular Weight | 387.36 |
| SMILES | O=C(C1=CC=C2N=C(N(C3(COC3)C)C2=C1)C4=C(F)C(O)=C(O)C(OC)=C4)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.