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TREX1-IN-3

TREX1 Inhibitor

TREX1-IN-3 is a potent inhibitor of TREX1 and TREX2, exhibiting an IC50 value for TREX1 of less than 0.1 μM and for TREX2 of less than 1 μM. Additionally, it displays an EC50 of less than 1 μM in HCT116 cancer cell lines. This compound is applicable in cancer research, providing valuable insights into the roles of TREX1 and TREX2 in tumor biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2588445-13-8
Applications	TREX1 Inhibitor
Formula	C₂₄H₁₉ClN₆O₄
Molecular Weight	490.90
SMILES	CN(C1=NC(C(NC2=CON=C2)=O)=C(C(N1C)=O)O)[C@@H](C3=C(C=CC=C3)Cl)C4=CC(C#N)=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.