Fig. 1 · Structure
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tri-GalNAc-COOH
ASGPR Ligand
tri-GalNAc-COOH functions as a ligand for the asialoglycoprotein receptor (ASGPR), enabling targeted delivery of therapeutics through receptor-mediated endocytosis. This compound is instrumental in lysosome-targeting chimera (LYTAC) research, aiding in the development of novel drug delivery systems and enhancing targeted therapeutic strategies. Its utility in cellular targeting makes it a valuable reagent for advancing studies in drug development and delivery mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1953146-81-0 |
| Applications | ASGPR Ligand |
| Formula | C75H134N10O35 |
| Molecular Weight | 1735.91 |
| SMILES | O=C(CCOCCOCCOCCOCCOCCC(O)=O)NC(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]1CO)[C@@H]([C@H]([C@H]1O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]2CO)[C@@H]([C@H]([C@H]2O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H](O[C@@H]3CO)[C@@H]([C@H]([C@H]3O)O)NC(C)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.