Fig. 1 · Structure
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Trichlormethiazide
Diuretic
Trichlormethiazide is an orally active thiazide diuretic primarily targeting the renal system to promote diuresis. This compound enhances urine volume and increases the excretion of sodium and potassium, with notable effects on improving creatinine clearance in models of acute renal failure. It is commonly utilized in research focused on hypertension and renal function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 133-67-5 |
| Applications | Diuretic |
| Formula | C8H8Cl3N3O4S2 |
| Molecular Weight | 380.66 |
| SMILES | O=S(C1=C(Cl)C=C(C2=C1)NC(C(Cl)Cl)NS2(=O)=O)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.