Triclabendazole-d3 is the deuterated form of Triclabendazole, a potent orally active antiparasitic agent. It exhibits significant anti-Leishmania activity and promotes gasdermin E (GSDME)-dependent pyroptosis through the activation of caspase-3. This stable isotope-labeled compound is valuable for investigating the effects of Triclabendazole on Fasciola hepatica and studying its biochemical pathways in parasitic infections.
Triclabendazole-d3 is the deuterated form of Triclabendazole, a potent orally active antiparasitic agent. It exhibits significant anti-Leishmania activity and promotes gasdermin E (GSDME)-dependent pyroptosis through the activation of caspase-3. This stable isotope-labeled compound is valuable for investigating the effects of Triclabendazole on Fasciola hepatica and studying its biochemical pathways in parasitic infections.
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