Fig. 1 · Structure
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TriGalNAc CBz
ASGPR Ligand
TriGalNAc CBz is a GalNAc derivative that functions as a ligand for the asialoglycoprotein receptor (ASGPR). It demonstrates significant potential for applications in mRNA drug delivery and lysosomal targeted chimerism (LYTAC) studies, facilitating the development of innovative therapeutic strategies. This compound is critical for research exploring targeted delivery mechanisms in gene therapy and intracellular trafficking.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 186613-57-0 |
| Applications | ASGPR Ligand |
| Formula | C34H35NO11 |
| Molecular Weight | 633.64 |
| SMILES | O=C(C1=CC=CC=C1)O[C@H]2[C@H]([C@H](O[C@H]([C@@H]2NC(C)=O)OCCCCC(O)=O)COC(C3=CC=CC=C3)=O)OC(C4=CC=CC=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.