TRIM is a potent nitric oxide synthase (NOS) inhibitor, selectively targeting neuronal nitric oxide synthase (nNOS) in mouse cerebellar samples and inducible nitric oxide synthase (iNOS) in rat lung tissues, with IC50 values of 28.2 µM and 27.0 µM, respectively. This compound exhibits significant antidepressant and anxiolytic-like properties, making it valuable for research into depression and anxiety disorders. TRIM serves as an important tool for investigations into NOS-related pathways and their implications in neuropsychiatric conditions.
TRIM is a potent nitric oxide synthase (NOS) inhibitor, selectively targeting neuronal nitric oxide synthase (nNOS) in mouse cerebellar samples and inducible nitric oxide synthase (iNOS) in rat lung tissues, with IC50 values of 28.2 µM and 27.0 µM, respectively. This compound exhibits significant antidepressant and anxiolytic-like properties, making it valuable for research into depression and anxiety disorders. TRIM serves as an important tool for investigations into NOS-related pathways and their implications in neuropsychiatric conditions.
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