Fig. 1 · Structure

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TRIM25 ligand-1

TRIM25 Covalent Ligand

TRIM25 ligand-1 is a covalent ligand that specifically targets the Cys498 residue in the PRYSPRY domain of TRIM25. By enhancing the auto-ubiquitination activity of TRIM25, it serves as a valuable tool for investigating the role of TRIM25 in cellular processes. Its selectivity for TRIM25 both in vitro and in live cells makes it suitable for research applications focusing on ubiquitin-mediated signaling pathways and immune response mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 3111776-36-1
Applications TRIM25 Covalent Ligand
Formula C21H23ClN2O2
Molecular Weight 370.87
SMILES
CC1=CC(C(N2CCN(C(CCl)=O)CCC2)=O)=CC=C1C3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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