Fig. 1 · Structure
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Trimazosin
α1-adrenoceptors Blocker
Trimazosin is an orally active quinazoline derivative that acts as a selective blocker of α1-adrenoceptors. It exhibits significant hypotensive effects through its modulation of vascular smooth muscle contraction, leading to reduced peripheral resistance. This compound is primarily utilized in cardiovascular research to investigate the mechanisms of hypertension and to evaluate potential therapeutic applications for related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 35795-16-5 |
| Applications | α1-adrenoceptors Blocker |
| Formula | C20H29N5O6 |
| Molecular Weight | 435.47 |
| SMILES | O=C(N1CCN(CC1)C2=NC3=C(C=C(C(OC)=C3OC)OC)C(N)=N2)OCC(C)(C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.