Trimebutine (3-TCBS) is a novel hydrogen sulfide (H2S) releasing reagent that combines trimebutine with phenyl 3-thiocarbamate to enhance anti-nociceptive properties. It demonstrates significant efficacy in reducing visceral pain and discomfort in vivo, particularly in a mouse colonic distension model. This compound’s ability to release H2S in a dose-dependent manner suggests its potential for research applications focused on pain management and gastrointestinal disorders.
Trimebutine (3-TCBS) is a novel hydrogen sulfide (H2S) releasing reagent that combines trimebutine with phenyl 3-thiocarbamate to enhance anti-nociceptive properties. It demonstrates significant efficacy in reducing visceral pain and discomfort in vivo, particularly in a mouse colonic distension model. This compound’s ability to release H2S in a dose-dependent manner suggests its potential for research applications focused on pain management and gastrointestinal disorders.
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