Fig. 1 · Structure
Documents & Downloads
Trimelamol
DNA Cross-Linker
Trimelamol is an effective DNA interstrand cross-linker that operates through acid-catalyzed mechanisms. Exhibiting notable anti-tumor activity, it demonstrates the ability to overcome platinum resistance, making it a significant candidate for cancer therapeutics. Current research applications primarily focus on its potential in treating lung and ovarian cancers. Due to its limited blood-brain barrier penetration, Trimelamol exhibits low neurotoxicity, enhancing its safety profile in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 64124-21-6 |
| Applications | DNA Cross-Linker |
| Formula | C9H18N6O3 |
| Molecular Weight | 258.28 |
| Synonyms | CB 10-375; NSC 283162 |
| SMILES | OCN(C1=NC(N(C)CO)=NC(N(C)CO)=N1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.