Fig. 1 · Structure

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Trimethaphan camsylate

Antihypertensive

Trimethaphan camsylate is a ganglionic blocker that primarily targets nicotinic acetylcholine receptors, leading to significant antihypertensive effects. This compound has demonstrated efficacy in lowering arterial blood pressure and may reduce pulmonary venous pressure in models of pulmonary edema. Its use in research applications includes studying cardiovascular dynamics and evaluating treatments for hypertension-related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 68-91-7
Applications Antihypertensive
Formula C32H40N2O5S2
Molecular Weight 596.80
Synonyms Ro 2-2222; Thiophanium derivatives
SMILES
O=C1N(CC2=CC=CC=C2)C(C[S+]3C4CCC3)C4N1CC5=CC=CC=C5.O=S(C[C@@]67C(C)([C@@](CC7)([H])CC6=O)C)([O-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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