Trimethyl chitosan is a multifunctional polymer derived from chitosan, predominantly functioning as an absorption enhancer. It targets the proteins associated with tight junctions in intestinal and mucosal epithelial cells, facilitating the rearrangement of tight junction proteins and increasing intercellular permeability. This characteristic significantly enhances the transmembrane transport of hydrophilic drugs, including peptides and proteins, making trimethyl chitosan an effective agent for drug delivery systems and the synthesis of nanoparticles in pharmaceutical research.
Trimethyl chitosan is a multifunctional polymer derived from chitosan, predominantly functioning as an absorption enhancer. It targets the proteins associated with tight junctions in intestinal and mucosal epithelial cells, facilitating the rearrangement of tight junction proteins and increasing intercellular permeability. This characteristic significantly enhances the transmembrane transport of hydrophilic drugs, including peptides and proteins, making trimethyl chitosan an effective agent for drug delivery systems and the synthesis of nanoparticles in pharmaceutical research.
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