Fig. 1 · Structure
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Trimidox hydrochloride
Ribonucleotide Reductase Inhibitor
Trimidox hydrochloride is a potent ribonucleotide reductase inhibitor, demonstrating significant antileukemic activity. This compound effectively inhibits the proliferation of human promyelocytic leukemia HL-60 cells, exhibiting an IC50 of 35 μM. It serves as a valuable research tool for studying ribonucleotide metabolism and its implications in leukemia treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 95933-75-8 |
| Applications | Ribonucleotide Reductase Inhibitor |
| Formula | C7H9ClN2O4 |
| Molecular Weight | 220.61 |
| Synonyms | VF-233 hydrochloride |
| SMILES | N=C(C1=CC(O)=C(O)C(O)=C1)NO.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.