Fig. 1 · Structure
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Tripartin
Histone Demethylase Inhibitor
Tripartin is a potent inhibitor of histone demethylases, specifically targeting the histone H3 lysine 9 demethylase KDM4. Inhibition of KDM4 has been shown to alter histone methylation states, thereby influencing gene expression and cellular differentiation. This reagent is valuable for research applications focused on epigenetic regulation, chromatin dynamics, and the role of histone modifications in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1428962-73-5 |
| Applications | Histone Demethylase Inhibitor |
| Formula | C10H8Cl2O4 |
| Molecular Weight | 263.07 |
| SMILES | O=C1C[C@@](O)(C(Cl)Cl)C2=C1C=C(O)C=C2O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.