Fig. 1 · Structure
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Triptolide palmitate
Triptolide Derivative
Triptolide palmitate is a derivative of Triptolide that targets cancer cells through its cytotoxic properties. It demonstrates significant inhibitory effects on MCF-7 and A549 cancer cell lines, with IC50 values of 7.5 and 6.4 μM, respectively. Additionally, Triptolide palmitate has a half-life (T1/2) of 50.4 minutes in Sprague Dawley rats, indicating its potential for drug delivery applications in cancer therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2126920-51-0 |
| Applications | Triptolide Derivative |
| Formula | C36H54O7 |
| Molecular Weight | 598.81 |
| SMILES | C[C@@]12[C@@]34[C@@]5([C@@](C[C@@]1([H])C6=C(C(OC6)=O)CC2)([H])O5)[C@@H]([C@@]7([C@](O7)([H])[C@]3([H])O4)C(C)C)OC(CCCCCCCCCCCCCCC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.