Fig. 1 · Structure
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TRK-IN-14
TRK Inhibitor
TRK-IN-14 is a potent TRK inhibitor that targets tropomyosin receptor kinases, which are key regulators of cell growth and differentiation. By modulating TRK signaling pathways, this compound demonstrates significant biological activity, making it a valuable tool for investigating TRK-related diseases. Researchers can utilize TRK-IN-14 to explore the therapeutic potential and mechanistic insights into conditions associated with aberrant TRK activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1365212-84-5 |
| Applications | TRK Inhibitor |
| Formula | C24H21F2N5O |
| Molecular Weight | 433.45 |
| SMILES | FC(C=C1)=CC=C1CNC(C2=CN=C3N2N=C(N4[C@](C5=CC(F)=CC=C5)([H])CCC4)C=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.