Fig. 1 · Structure
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TRK-IN-16
TRK Inhibitor
TRK-IN-16 is a potent TRK inhibitor that targets tropomyosin receptor kinases, which are essential for regulating cell growth, differentiation, and various cellular signaling pathways. This compound exhibits significant biological activity in inhibiting TRK-mediated signal transduction, making it a valuable tool for research into TRK-related diseases. Its application spans studies focused on cancer therapies and other conditions linked to aberrant TRK signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1365212-81-2 |
| Applications | TRK Inhibitor |
| Formula | C19H20FN5O |
| Molecular Weight | 353.39 |
| SMILES | O=C(C1=CN=C2C=CC(N3CCCC3C4=CC(F)=CC=C4)=NN21)NCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.