Fig. 1 · Structure
Documents & Downloads
TRK-IN-18
TRK Inhibitor
TRK-IN-18 is a potent inhibitor of tropomyosin-related kinases (Trks), a family of receptor tyrosine kinases that mediate cellular responses to neurotrophins such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). This compound demonstrates significant potential in cancer research by disrupting the signaling pathways of Trk activation, which are implicated in various tumorigenic processes. TRK-IN-18 serves as a valuable tool for elucidating the role of Trks in cancer biology and for the development of targeted therapeutics.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2412008-91-2 |
| Applications | TRK Inhibitor |
| Formula | C25H23F2N5O2S |
| Molecular Weight | 495.54 |
| SMILES | CSC1=C(C=C(C=C1)F)[C@H]2C[C@@H](CN2C3=NN4C(C(NCC5=CC(O)=CC=C5)=O)=CN=C4C=C3)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.