Trk-IN-4

Name: Trk-IN-4
Brand: Adooq Bioscience
SKU: A19277
Rating: 5 (288 reviews)

Catalog No.: A19277

pan-Trk inhibitor

Trk-IN-4 (PF-6683324 isomer) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect.

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Grouped product items
Size	Price	Stock
1mg	$40.00	In stock
5mg	$100.00	In stock
10mg	$180.00	In stock
25mg	$405.00	In stock
50mg	$685.00	In stock
100mg	$1,200.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Trk-IN-4 (PF-6683324 isomer) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect.

Targets

Target	Value

Product Information

Catalog Num	A19277
Formula	C24H23F4N5O4
Molecular Weight	521.46
CAS Number	1799788-94-5
SMILES	O=C(N)C1=C(O[C@H]2CCN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C[C@H]2F)N=CC(C4=CN(C)C=N4)=C1
Synonyms	PF-6683324 isomer
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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